What is Donor Horse Serum?
Donor Horse Serum (DHS), or Equine Serum, is a nutrient-rich fluid derived from the blood of controlled horse herds- but does not contain red blood cells or other clotting components. Donor Horse Serum has higher protein and less trace metals than Fetal Bovine Serum (FBS), and can be used as an alternative to FBS in certain applications
How is Donor Horse Serum (DHS) Made?
Donor Horse Serum is sourced from healthy horse herds that are regularly inspected and tested for infections equine diseases, including Equine Infectious Anemia (EIA) .
Biologos’ quality control testing, tests for microbiological abnormalities, such as the presence of bacterial, fungal, and mycoplasma contamination and viruses. Serum is also tested for adventitious agents using modified procedures from the Code of Federal Regulations, Title 9, Section 113.53 (“Requirements for Ingredients of Animal Origin”). Once the absence of contamination has been confirmed and approved, batches of serum are prepared for the packaging and distribution process.
The packaging process begins with serum being thawed under controlled conditions and sterile filtered. Sterile filtration involves the serums being filtered through a series of filters in descending pore size, utilizing 0.1 micron filters for the final filtration step. Filling takes place in a laminar flow hood and a certified clean room to maintain ISO Class 5 conditions. The serum is aseptically dispensed into gamma irradiated, sterile PETG or HDPE bottles and LDPE bioprocess bags (20-100 liter capacity). Filled containers are then labeled, frozen, and maintained at temperatures less than -5°C to preserve the product quality.
Donor Horse Serum Storage and Handling
Donor Horse Serum can be supplied in gamma irradiated, sterile PETG or HDPE bottles and LDPE bioprocess bags (20-100 liter capacity). We recommend that the serum be stored frozen at a temperature of -5°C to -20°C. Multiple freeze-thaw cycles of the serum should be avoided as this may lead to deterioration of the product. Always use aseptic techniques when handling the serum and aliquot into sterile containers.