Fetal Bovine Serum (FBS)

Fetal Bovine Serum (FBS) is a commonly used media supplement for cells in culture. Fetal Bovine Serum (FBS) has excellent cell growth characteristics, low endotoxin, low hemoglobin values and is ideal for research that is reliant on growth of cell lines.

Collection and Processing:


The Fetal Bovine Serum used by Biologos meets all of the USDA requirements for animal products. All FBS Media is traceable back to the date and location of collection. In addition, all of the Fetal Bovine Serum used for processing must meet Biologos’ strict quality requirements for raw material.


Approved lots of raw Fetal Bovine Serum are thawed under controlled conditions and sterile filtered by a process that uses a series of filters in descending pore size, utilizing 0.1 micron filters for the final filtration step. Filling takes place in a laminar flow hood and clean room certified to maintain ISO Class 5 conditions. The Fetal Bovine Serum is aseptically dispensed into gamma irradiated, sterile PETG or HDPE bottles. Filled containers are labeled, frozen, and then maintained at temperatures less than -5oC to preserve the product quality.

Quality Control Testing

Microbiological Testing:

Each lot of Fetal Bovine Serum is tested to confirm the absence of bacterial or fungal contamination. Each lot of FBS Media is also tested to confirm the absence of mycoplasma contamination.

Virus Testing:

The fetal Bovine Serum is additionally tested for adventitious agents using modified procedures adapted from the Code of Federal Regulations, Title 9, Section 113.53, “Requirements for Ingredients of Animal Origin”.

Storage and Handling

The FBS Media is shipped in gamma irradiated, sterile PETG or HDPE bottles. Biologos recommends that the Fetal Bovine Serum be stored frozen at a temperature of -5oC to -20oC. Multiple freeze-thaw cycles of the serum should be avoided as this may lead to deterioration of the product.


Fetal Bovine Serum (FBS) is shipped frozen by freezer truck or next day air in insulated containers packed with dry ice.

Industry Uses for Fetal Bovine Serum (FBS)

There is a wide range of use for Fetal Bovine Serum. One important application is in the pharmaceutical field, where it is used to research, manufacture and control human and veterinary vaccines. Fetal Bovine Serum is also used extensively for research in Universities and Labs.  Fetal Bovine Serum is extensively used in cell culture as a media supplement to culture the growth of cell lines.

What is Fetal Bovine Serum?

Fetal Bovine Serum (FBS) is the clear, orange fluid that is obtained from separating blood, sourced from a calf (bovine) fetus, in to its solid and liquid components. Fetal Bovine Serum is among most widely used serum-supplement for cell culture because of it’s valuable growth characteristics. FBS has a very low level of antibodies and contains more growth factors than other types of sera.

What is Fetal Bovine Serum Used For?

Fetal Bovine Serum (FBS) is primarily used as a cell culture media supplement in research and development of pharmaceuticals.

Why is Fetal Bovine Serum Important?

Fetal Bovine Serum is important because of its cell growth characteristics. When it is imperative to have guaranteed growth of cell lines, FBS is typically used.

Who Uses Fetal Bovine Serum?

Fetal Bovine Serum (FBS) is primarily used by laboratories in the pharmaceutical industry as well as University labs.

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