Porcine Serum

Product Overview

Porcine (Pig or Swine) serum is the clear, red-orange fluid that is obtained from separating blood, sourced from pigs, in to its solid and liquid components. Porcine Serum, like other animal sera, can be used as a supplement to basal growth medium in cell culture. Sera, like porcine serum, is an important component of cell culture media. It serves as a source for amino acids, proteins, fat-soluble vitamins (such as A, D, E, and K), carbohydrates, lipids, hormones, growth factors, minerals, and additional trace elements.


Each batch of serum meets the USDA standards for animal products, Biologos’ standard for raw materials, is traceable to date and collection location, and is processed using:

  • Sterile filtering
  • Irradiation
  • Heat inactivation

Porcine Serum is most commonly in the fields of Immunology and Biochemistry as a cell culture medium and to aid in vaccine production.

Additional Information:

What is Porcine Serum?
How is Porcine Serum Made?
Porcine Serum Storage and Handling
Porcine Serum Uses

What is Porcine Serum?

Porcine (Pig) Serum is a nutrient-rich fluid derived from the blood of bovine fetuses- but does not contain red blood cells or other clotting components. FBS is composed of bovine serum albumin (BSA), a globular-protein and other proteins that support the growth, survival, and division of cultured cells.

How is Porcine Serum Made?

Porcine Serum is is collected from healthy pigs that are 1 year old or younger, then prepared and tested.

Biologos’ quality control testing, tests for microbiological abnormalities, such as the presence of bacterial, fungal, and mycoplasma contamination and viruses. Serum is also tested for adventitious agents using modified procedures from the Code of Federal Regulations, Title 9, Section 113.53 (“Requirements for Ingredients of Animal Origin”). Once the absence of contamination has been confirmed and approved, batches of serum are prepared for the packaging and distribution process.

The packaging process begins with serum being thawed under controlled conditions and sterile filtered. Sterile filtration involves the serums being filtered through a series of filters in descending pore size, utilizing 0.2 micron filters for the final filtration step. Filling takes place in a laminar flow hood and a certified clean room to maintain ISO Class 5 (FED STD 209E equivalent Class 100) cleanroom conditions. The serum is aseptically dispensed into gamma irradiated, sterile PETG or HDPE bottles and LDPE bioprocess bags (20-100 liter capacity).. Filled containers are then labeled, frozen, and maintained at temperatures less than -5°C to preserve the product quality.

Porcine Serum Storage and Handling

The Porcine Serum can be supplied in gamma irradiated, sterile PETG or HDPE bottles and LDPE bioprocess bags (20-100 liter capacity). We recommend that the serum be stored frozen at a temperature of -5°C to -20°C. Multiple freeze-thaw cycles of the serum should be avoided as this may lead to deterioration of the product. Always use aseptic techniques when handling the serum and aliquot into sterile containers.

Porcine Serum Uses

Porcine Serum is typically used in the fields of Immunology and Biochemistry, the most common applications are:

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